As of Monday afternoon, around 600 people were still missing in Asheville, North Carolina, as the city grapples with extensive damage from washed-out roads, collapsed bridges, communication breakdowns, and widespread power outages, Mayor Esther Manheimer informed CNN.

The severe destruction has crippled the city’s infrastructure, isolating numerous remote areas and hindering rescue teams from delivering critical supplies, Manheimer explained during an interview on “The Source” Monday night.

“Our main focus right now is reaching those who are still cut off,” Manheimer told CNN’s Kaitlan Collins. “However, we are also dealing with major water and power shortages in most parts of the city, and we urgently require resources such as clean water, food, and other essential items.”

Describing the impact of Helene on the city as “catastrophic,” the mayor added, “Photos don’t fully convey the scale of the damage.”

President Joe Biden is set to fly over the city on Wednesday to survey the destruction, she noted.